The Juan O’Gorman mosaic mural commissioned for the 1968 World’s Fair, known as HemisFair, is located on the exterior façade of the Lila Cockrell Theater. The 130-foot long mural is titled “Confluence of Civilizations in the Americas” and it was one of three murals that still remain installed at the Henry B. Gonzalez Convention Center. The mural illustrates the theme of HemisFair 68′ and includes imagery such as Adam & Eve, European immigration to the United States and Mexico and indigenous cultures of the Mesoamerican civilization. It was created with about 500 panels equaling approximately 400,000 pieces of colored stones. The mural was renovated and repaired in 2022.

O’Gorman was a muralist, painter, mosaic artist, professor and architect whose career was spent mostly in Mexico.